Electrophilic aromatic iodination of vanillin purpose: the purpose of this laboratory experiment is for an aromatic compound to undergo an electrophilic substitution reaction. Both proceeding by electrophilic aromatic substitution in iodination iodine, hydroiodic acid and alkali hypoiodites vanillin, bezaldehyde, acetic acid. Vanillin is a phenolic aldehyde, which is an organic compound with the molecular formula c 8 h 8 o reacts with glyoxylic acid by electrophilic aromatic. Electrophilic aromatic iodination of vanillin essay electrophilic aromatic iodination of vanillin purpose: the purpose of this laboratory experiment is for an aromatic compound to undergo an electrophilic substitution reaction.
Lignin derived aromatic compounds are frequently inexpensive precursors of a number of valuable organic substances for example, vanillin is an important precursor chemical of 3,4,5-trimethoxybenzaldehyde, a chemical of well known importance to the pharmaceutical industry. I) title: experiment 12 electrophilic aromatic iodination ii) introduction: the purpose of this lab was to perform an aromatic iodination reaction, called electrophilic iodination, transforming vanillin to 5-iodovanillin. Electrophilic aromatic substitution is the most typical reaction of benzene and its deriva- tives as you learn about other electrophilic substitution reactions, it will help you to under. Organic chem help plz in electrophilic aromatic substitution lab we did iodination of vanillin to 5-iodovanillin we used vanillin, ethanol, sodium iodide, sodium hypochlorite, sodium thosulfate, and hcl.
Electrophilic aeromatic substitution of vanillin to 5-iodovanillin is a process that requires careful steps to obtain an accurate recovery the experiment appears to be very inefficient in the processes above. Introduction there are a number of methods available to perform electrophilic iodination on aromatic rings most methods involve using iodine and an oxidizing agent, such as nitric or periodic acids, and are not very environmentally friendly. Electrophilic aromatic iodination of vanillin bromination of stilbene one of the very first electrophilic addition reactions learned was bromination of an. Electrophilic aromatic substitution (eas) is a substitution reaction usually involving the benzene ring more specifically it is a reaction in which the hydrogen atom of an aromatic ring is replaced as a. Bromination of acetophenone, 2-acetothienone, while the activity of the electrophilic agent (br 2 + h2so4) could is directed predominantly to the aromatic ring.
Electrophilic substitution reaction involving the iodination of vanillin procedure: step 1: in a 100 ml round bottom flask containing a magnetic stir bar, dissolve 10 g of vanillin in 20 ml of ethanol. Ch338 - lab #1: electrophilic aromatic iodination post-lab report results from 10072 grams of vanillin and 11766 grams of ki, my lab partner and myself obtained 18403 grams of 5-iodovanillin as our crude product. Created date: 2/28/2011 1:47:48 pm. » questions » science/math » chemistry » physical chemistry » electrophilic iodination of vanillin para- directing in electrophilic aromatic substitution.
Electrophilic aromatic iodination of vanillin purpose: the purpose of this laboratory experiment is for an aromatic compound to undergo an electrophilic substitution reaction to carry this out, our method combines sodium iodide and common bleach as the oxidizing agent in aqueous alcohol as the solvent. Vanillin from glucovanillin chemicals and equipment : peaktime: sassy leaf oil: chemicals and equipment : easy aromatic iodination reference: chemistry discourse . Deactivated arenes were mono- or diiodinated with strong electrophilic i + reagents, which were prepared from naio 4 and either i 2 or ki in concentrated sulfuric acid, using either a 'direct' or an 'inverse' method of aromatic iodination to give mono- or diiodinated pure products in good yields.
Journal of the brazilian chemical society direct iodination of aromatic compounds is difficult due to the low electrophilicity of molecular iodine compared to. Properties of vanillinpdf aromatic iodination of vanillin: mechanism of vanillin: these reactions occur two-step addition/elimination mechanism forming a. Presumably, the oxidized iodine species generated by laccase catalysis act as electrophiles for the electron-dense aromatic rings of vanillin and related compounds, similar to the mechanism suggested for conventional iodination methods elucidation of the exact sequence of events and the molecular mechanisms governing the interactions of. Electrophilic iodine species such laccase-catalyzed iodination of vanillin and related compounds as electrophiles for the electron-dense aromatic rings of.